Cyclic HIV Protease Inhibitors: Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas
- 1 January 1996
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 39 (18) , 3514-3525
- https://doi.org/10.1021/jm9602571
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Three‐dimensional solution structure of the HIV‐1 protease complexed with DMP323, a novel cyclic urea‐type inhibitor, determined by nuclear magnetic resonance spectroscopyProtein Science, 1996
- Effect of grapefruit juice on blood cyclosporin concentrationThe Lancet, 1995
- Update on a proteinase inhibitorAIDS, 1994
- Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic InhibitorsJournal of Medicinal Chemistry, 1994
- The Entropic Cost of Bound Water in Crystals and BiomoleculesScience, 1994
- Nonpeptide HIV protease inhibitors designed to replace a bound waterBioorganic & Medicinal Chemistry Letters, 1993
- STRUCTURE-BASED INHIBITORS OF HIV-1 PROTEASEAnnual Review of Biochemistry, 1993
- Synthesis of C2-symmetric HIV-1 protease inhibitors from D-mannitolBioorganic & Medicinal Chemistry Letters, 1992
- Cholinergic activity of acetylenic imidazoles and related compoundsJournal of Medicinal Chemistry, 1991
- Magnesium amide bases and amido-Grignards. 1. Ortho magnesiationJournal of the American Chemical Society, 1989