Oral corticosteroids in the treatment of ocular myasthenia gravis

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Abstract
Eight patients with ocular myasthenia gravis unresponsive to anticholines-terase medications were treated with alternate-day prednisone. Seven of the eight showed significant and sustained improvement. The patients exhibited few side effects of steroid therapy, and none manifested neurologic deterioration after institution of the therapy. Since anticholines-terase medications fail to benefit most patients with ocular myasthenia and since these agents reportedly have long-term undesirable effects on the neuromuscular junction, oral prednisone is proposed as an alternative therapy for ocular myasthenia.

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