Effect of Prostaglandin E1 on Blood Pressure, Heart Rate and Concentration of Free Fatty Acids of Plasma in Man.

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Abstract
Summary Infusions of PGE1 to human subjects caused an increase in heart rate and in concentration of FFA and glycerol in plasma. When PGE1 was infused intravenously together with norepinephrine the nor-epinephrine induced increase in blood pressure was reduced and the bradycardia was abolished. The increase in concentration of FFA and glycerol in plasma caused by norepinephrine was, however, only slightly reduced by PGE1.