Dsc Screening for Drug-Drug Interactions in Poly Pharmaceuticals Intended for the Alleviation of the Symptoms of Colds and Flu. II.
- 1 January 1987
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 13 (2) , 345-354
- https://doi.org/10.3109/03639048709040177
Abstract
DSC screening for drug-drug interactions of a polypharmaceutical capsule dosage form containing salicylaminde, ascorbic acid, pyrilamine maleate and phenylephrine hydrochloride was performed. The results show the following: 1. Ascorbic acid is incompatible with salicylamide, pyrilamine maleate and pheynylephrine hydrochloride. 2. Salicylamide is incompatible with ascorbic acid, pyrilamine maleate and phenylephrine hydrochloride. 3. Pyrilamine maleate is incompatible with ascorbic acid, salicylamide and phenylephrine hydrochloride. 4. Phenylephrine hydrochloride is incompatible with salicylamide, pyrilamine maleate and ascorbic acid.This publication has 2 references indexed in Scilit:
- Degradation of Phenylephrine Hydrochloride in Tablet Formulations Containing AspirinJournal of Pharmaceutical Sciences, 1964
- Tablets of Pyrilamine Resin Adsorbate with Aspirin and Vitamin CJournal of Pharmaceutical Sciences, 1962