INSANITIES CAUSED BY ACUTE AND CHRONIC INTOXICATIONS WITH OPIUM AND COCAIN.

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Abstract
During the last seven years I have been collecting cases of intoxication with morphin and cocain. The majority are cases observed in hospitals. Confining myself to the effect of the drugs on the cerebral functions, and especially on the mentality, I am able to divide the 171 cases into two groups, viz.: 80 of acute and 91 of chronic poisoning. The first group comprises 60 cases of morphin, 15 of cocain and 5 of mixed intoxication. The second group is composed of 70 morphin habitués, 10 cocain habitués and 11 patients with mixed intoxication. The permanent effect of the poison did not depend altogether on the mode of its administration or amount absorbed. For a normal adult 6 or 7 cgm. hypodermically constitute a toxic dose, but individual susceptibility should be taken into consideration. Cases of recovery have been reported even with doses of 75 cgm. of morphin. Habit is

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