The Threat of Instability: Neurodegeneration Predicted by Protein Destabilization and Aggregation Propensity
Open Access
- 29 July 2008
- journal article
- editorial
- Published by Public Library of Science (PLoS) in PLoS Biology
- Vol. 6 (7) , e193
- https://doi.org/10.1371/journal.pbio.0060193
Abstract
A new method based on protein stability and aggregation propensity reveals a strong correlation between the properties of mutant Cu/Zn-superoxide dismutases associated with amyotrophic lateral sclerosis and patient survival.Keywords
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