Antibodies to Chlamydia trachomatis in Cervicovaginal Secretions
- 1 January 1980
- journal article
- research article
- Published by Wolters Kluwer Health in Sexually Transmitted Diseases
- Vol. 7 (1) , 11-15
- https://doi.org/10.1097/00007435-198001000-00003
Abstract
Concentrated cervicovaginal washings obtained from women attending a venereal disease clinic were tested for Chlamydia-specific immunoglobulins (Ig) by a single-antigen, indirect immunofluorescence technique. Chlamydial antibodies [Ab] (IgA and/or IgG) were present in washings from 22 (42%) of 52 patients tested. These Chlamydia-specific Ab were significantly (P < 0.001) associated with Chlamydia-specific Ab in serum. The former Ab may have been derived from the serum rather than synthesized in the cervix. The association between chlamydial Ab in cervicovaginal washings and isolation of Chlamydia from the cervix was much weaker. The diagnostic value of detection of Chlamydia-specific Ab in sera and in cervical secretions is questionable.This publication has 1 reference indexed in Scilit:
- Antibodies to Candida albicans in human cervicovaginal secretions.Sexually Transmitted Infections, 1977