Deoxyribonuclease Activity Associated with Adenovirus 5 and 7

Abstract
A DNase activity was associated with isolated components of adenovirus types 5 and 7. The enzymatic activity was associated with the purified virus and viral components extracted from the soluble material of infected [human cervical carcinoma HeLa] cells. The DNase activity of adenovirus type 5 was maximum at pH 5.5 and 7.0, but that of adenovirus 7 was active only at pH 7.0. Both DNases were located in the penton fraction.