Long chain analogs of physostigmine as potential drugs for Alzheimer's disease: new insights into the mechanism of action in the inhibition of acetylcholinesterase
- 1 November 1997
- journal article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
- Vol. 1343 (1) , 41-50
- https://doi.org/10.1016/s0167-4838(97)00133-7
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Molecular and cellular biology of cholinesterasesPublished by Elsevier ,2003
- Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and TrpScience, 1996
- Synthesis and structure-activity relationships of new acetylcholinesterase inhibitors: Morpholinoalkylcarbamoyloxyeseroline derivativesBioorganic & Medicinal Chemistry Letters, 1995
- Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.Proceedings of the National Academy of Sciences, 1993
- A Controlled Trial of Tacrine in Alzheimer's DiseaseJAMA, 1992
- Physostigmine analogs anticholinesterases: effects of the lengthening of the N-carbamic chain of the inhibition kineticsBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1992
- Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase CJournal of Molecular Biology, 1988
- Pharmacokinetics and pharmacodynamics of physostigmine after intravenous administration in beagle dogsNeuropharmacology, 1987
- The Cholinergic Hypothesis of Geriatric Memory DysfunctionScience, 1982
- A new and rapid colorimetric determination of acetylcholinesterase activityBiochemical Pharmacology, 1961