EFFECT OF PROGESTERONE ON THE OVARIES AND EMBRYOS OF MICE IN EARLY PREGNANCY1,2
- 1 April 1942
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 30 (4) , 619-622
- https://doi.org/10.1210/endo-30-4-619
Abstract
The effects of progesterone injected during early pregnancy in the albino mouse differ from those reported by others for the second half of pregnancy. Daily injs. of 1.0 mg. of progesterone, begun the day of mating, prevent implantation. Implantation occurs if these injs. are delayed until the 2d day after mating. The embryos continue to grow during the period of injs. but die within a few days after progesterone is withheld. The corpora lutea show definite signs of regression. This condition is probably due to an inadequate supply of estrogen. These effects of progesterone on the ovary and embryos in early pregnancy are similar to those reported previously after injs. of desoxycortico-sterone acetate.Keywords
This publication has 4 references indexed in Scilit:
- THE EFFECT OF DESOXYCORTICOSTERONE ACETATE ON EARLY PREGNANCY1Endocrinology, 1941
- The effect of progesterone on the mouse ovary as influenced by gestationThe Anatomical Record, 1939
- Maintenance of pregnancy in the hypophysectomized rabbit by the administration of oestrinThe Journal of Physiology, 1939
- Quantitative data on the inhibition of œstrus by testosterone, progesterone, and certain other compoundsThe Journal of Physiology, 1938