Investigation of an incidental finding of eosinophilia

Publisher Website
Google Scholar
Abstract
The causes of eosinophilia fall into three categories (reactive disorders, clonal disorders of the bone marrow, and hypereosinophilic syndrome). This article outlines the appropriate use of investigations to establish the cause of eosinophilia #### Learning points A 57 year old man presented to his general practitioner with symptoms of a persistent dry cough and general fatigue. He had no notable medical history; he was a non-smoker and was not taking any regular medication. Clinical examination was unremarkable. A full blood count showed haemoglobin 141 g/L (normal range 130-180 g/L), mean cell volume 92 fL (80-100 fL), platelets 178×109/L (150-400×109/L), and leucocytes 9×109/L (4-13×109/L). The leucocyte differential showed neutrophils 4.3×109/L (2-8×109/L), lymphocytes 3×109/L (1-4×109/L), monocytes 0.5×109/L (0.2-0.8×109/L), and eosinophils 8.2×109/L (0.1-0.6×109/L). The blood film confirmed the presence of the eosinophilia and the eosinophil morphology appeared normal. Red cells, other leucocytes, and platelets were also morphologically normal. On the basis of the blood appearances the reporting haematologist favoured a reactive cause for the eosinophilia (such as infection, allergy, and hypersensitivity disorders; vasculitis; and autoimmune disorders). …

This publication has 0 references indexed in Scilit: