Abstract
To the Editor.— I would like to comment on the recent article by Pacheco-Romero et al (224:849, 1973), dealing with the relationship of spermagglutinating activity and female infertility. I fear that this report may cause some confusion, because we may question the reliability of the exact technics that were used, and also because of the logic of the design and the final interpretation concerning antibody importance. Regarding the interpretation, the most urgent point is that the authors did not include a population group of fertile women, although they did study two groups, namely, a group in whom infertility was of the unexplained variety and another group, in whom the infertility was explainable on some organic basis. They found a similar incidence of positive results in these two groups, and they concluded that the presence of spermagglutinins did not play an important role in female infertility. It might have been preferable

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