The Lack of Nerve Degeneration in Uncomplicated Vitamin B1 Deficiency in the Chick and the Rat

Publisher Website
Google Scholar
Abstract
The administration of β-carotene or percomorph oil together with riboflavin removed all evidence of pathology in the peripheral nerves of vitamin B1 deficient chicks or chicks fed an adequate ration at a restricted level of intake. Neuropathology was seldom observed in a rat on a vitamin B1 deficient but otherwise adequate diet. Recovery from B1 deficient symptoms in the rat by the administration of crystalline vitamin B1 produced a marked histologic reaction in the liver. It is concluded from these studies that uncomplicated beriberi is not accompanied by peripheral nerve degeneration.