Removal of Zinc from Humans by DTPA Chelation Therapy

Abstract
The urinary excretion of zinc in a patient treated by low dose (14 mg/kg per week)-long term DTPA administration was studied. Urinary zinc excretion during 24 hr after the i.v. infusion of Na3CaDTPA was 20–30 times greater than the mean daily zinc excretion during a period with no treatment. During the treatment period, the average weekly zinc excretion was increased 5 fold.

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