Occurrence of the Sandifer complex in the Brachmann‐de Lange syndrome
- 15 November 1993
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 47 (7) , 1026-1028
- https://doi.org/10.1002/ajmg.1320470719
Abstract
Gastroesophageal reflux is a common occurrence in infancy. The most severe complications of reflux include torticollis, opisthotonus, and paroxysmal dystonic posture (known as rhe Sandifer complex). We examined 17 patients now ranging in age from 9 months to 19 years (mean age 11 years) with the Brachmann-de Lange syndrome for evidence of gastroesophageal reflux and found that 13 had not only reflux, but also posturing and behavior consistent with the Sandifer complex. We propose that early recognition of gastroesophageal reflux in these patients may prevent the full picture of the Sandifer complex and allow for medical treatment rather than surgical intervention.Keywords
This publication has 2 references indexed in Scilit:
- Sandifer Syndrome ReconsideredActa Paediatrica, 1989
- Apparent G syndrome presenting as neck and upper limb dystonia and severe gastroesophageal refluxAmerican Journal of Medical Genetics, 1987