Cardiovascular Effects of Anesthetic Induction with Ketamine

Publisher Website
Google Scholar
Abstract
Es in ventricular contractility, and four had decreases in cardiac output. Mean arterial blood pressure decreased in four patients. Pulmonary venous admixture increased in four of six patients, while oxygen consumption decreased in eight of 11 patients. Thus, a single dose of ketamine produced decreases in cardiac and pulmonary performance and in peripheral oxygen transport in this group of patients. It is proposed that in severely ill patients, preoperative stress may alter the usual physiologic responses to ketamine administration, and adverse effects may predominate. Ketamine, therefore, should be used with caution for induction of anesthesia in critically ill and in acutely traumatized patients until additional studies and further information on cardiovascular responses to ketamine are available. Reprint requests to Dr. Shoemaker, Department of Surgery, Los Angeles County Harbor/UCLA Medical Center, 1000 West Carson Street, Torrance, California 90509. Accepted for publication January 22, 1980. © 1980 International Anesthesia Research Society...

This publication has 0 references indexed in Scilit: