Semiconductor Nanocrystals as Fluorescent Biological Labels
- 25 September 1998
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 281 (5385) , 2013-2016
- https://doi.org/10.1126/science.281.5385.2013
Abstract
Semiconductor nanocrystals were prepared for use as fluorescent probes in biological staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have a narrow, tunable, symmetric emission spectrum and are photochemically stable. The advantages of the broad, continuous excitation spectrum were demonstrated in a dual-emission, single-excitation labeling experiment on mouse fibroblasts. These nanocrystal probes are thus complementary and in some cases may be superior to existing fluorophores.Keywords
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