In Vitro Characterization of the RP-6 Dialyzer: Co-Current and Counter-Current Clearance as a Function of Ultrafiltration
- 1 January 1979
- journal article
- research article
- Published by Taylor & Francis in Journal of Dialysis
- Vol. 3 (2-3) , 237-250
- https://doi.org/10.3109/08860227909063943
Abstract
Analytical and graphical techniques are described for presenting clearance data as a function of ultrafiltration; thus for the first time comparison of clearance values between dialyzers can be made unambiguously. This simple method uses a hand calculator to determine three coefficients. Clearance has been shown to be accurately described by the equation C = α1 + α2Qv + α3 (1/QBi). This formula permits construction of easily read families of curves which can predict clearance values under most clinical situations. The RP-6 dialyzer is characterized by these methods for clearance of urea, glucose and vitamin B12 for counter-current and co-current modes.Keywords
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