Structural Basis for Chk1 Inhibition by UCN-01

This publication has 20 references indexed in Scilit:

• Implications for Chk1 Regulation: The 1.7 Å Crystal Structure of Human Cell Cycle Checkpoint Kinase Chk1
  Cell, 2000
• The Chk1 Protein Kinase and the Cdc25C Regulatory Pathways Are Targets of the Anticancer Agent UCN-01
  Journal of Biological Chemistry, 2000
• Recent discovery and development of selective protein kinase C inhibitors
  Drug Discovery Today, 1996
• UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p53
  JNCI Journal of the National Cancer Institute, 1996
• Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.
  Proceedings of the National Academy of Sciences, 1996
• PROCHECK: a program to check the stereochemical quality of protein structures
  Journal of Applied Crystallography, 1993
• MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures
  Journal of Applied Crystallography, 1991
• Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase
  Science, 1991
• Improved methods for building protein models in electron density maps and the location of errors in these models
  Acta Crystallographica Section A Foundations of Crystallography, 1991
• Checkpoints: Controls That Ensure the Order of Cell Cycle Events
  Science, 1989