Malignant melanoma appearing in a post‐mastectomy lymphedematous arm: A novel association of double primary tumors

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Abstract
The association of a malignant melanoma appearing as an additional primary tumor in the swollen arm adjacent to a mastectomy for breast cancer is reported. A review of the literature revealed only one similar patient previously reported. In both patients, the melanoma and its metastasis were restricted to the lymphedematous arm, appeared 10 years post‐mastectomy, and responded to therapy. The similarity to Stewart‐Treves syndrome is emphasized. It is suggested that nevi developing in the lymphedematous arm post‐mastectomy should be carefully monitored and excised early whenever indicated.