S-(HYDROXYMETHYL) 4-HYDROXYPHENYL SULFIDES: SYNTHESIS AND SELECTED CHEMISTRY OF SOME STABLE HEMIMERCAPTALS
- 1 January 1987
- journal article
- research article
- Published by Taylor & Francis in Phosphorus and Sulfur and the Related Elements
- Vol. 29 (1) , 67-71
- https://doi.org/10.1080/03086648708072842
Abstract
The base-catalyzed reaction of 3,5-di-tert-butyl-4-hydroxybenzenethiol (1a), 3-tert-butyl-4-hydroxy-5-methylbenzenethiol (1b), and 4-hydroxybenzenethiol (1c) with formaldehyde gave the corresponding hemimercaptal derivatives 2a–c, respectively. The stable hemimercaptals 2a–c were characterized by IR, 1H NMR, 13C NMR, MS and elemental analysis. The ester of 2a with 3-(3,5-di-tert-butyl-4-hydroxy-phenyl)propanoic acid (3a) was prepared using triphenylphosphine and diethyl azodicarboxylate (Mitsunobu conditions).Keywords
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