Studies on the Serological Response in Sheep to Naturally Acquired Gastro-intestinal Nematodes. I. Preparation of Antigens and Evaluation of Serological Techniques

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Abstract
Antigens were prepared by low temperature methods to preserve “functional” antigen. These antigens showed marked cross reactivity and were satisfactory in complement fixation tests. The passive haemagglutination test using “functional” antigen gave titres which were higher than those obtained with the complement fixation test. High antibody titres were observed in sheep naturally infested with nematodes and a relationship between antibody titre and egg count was demonstrated.

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