ZnBr2-MEDIATED HIGHLY DIASTEREOSELECTIVE ADDITION OF GRIGNARD REAGENTS TO α-BENZYLOXY ALDEHYDES
- 5 August 1985
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 14 (8) , 1221-1222
- https://doi.org/10.1246/cl.1985.1221
Abstract
α-Benzyloxy aldehydes reacted with Grignard reagents in the presence of ZnBr2 to afford vicinal syn-diol derivatives with high diastereoselectivity.This publication has 8 references indexed in Scilit:
- Metal ion controlled addition to .alpha.,.beta.-dialkoxy carbonyl compoundsThe Journal of Organic Chemistry, 1985
- Doppelte Stereodifferenzierung und eine neue Strategie zur Stereokontrolle in der Organischen SyntheseAngewandte Chemie, 1985
- Chelat- oder Nicht-Chelat-Kontrolle bei Additionsreaktionen von chiralen α- und β-Alkoxycarbonyl-VerbindungenAngewandte Chemie, 1984
- Highly diastereocontrolled reduction of ketones by means of hydrosilanes. Practical synthesis of optically active 1,2-diols and 2-amino alcohols of threo or erythro configurationJournal of the American Chemical Society, 1984
- Preparation and determination of configurationally pure trans-(2S,3S)-2,3-epoxybutaneThe Journal of Organic Chemistry, 1980
- Chelation-controlled nucleophilic additions. 2. A highly effective system for asymmetric induction in the reaction of organometallics with β-alkoxyaldehydes.Tetrahedron Letters, 1980
- Chelation-controlled nucleophilic additions. 1. A highly effective system for asymmetric induction in the reaction of organometallics with α-alkoxyketones.Tetrahedron Letters, 1980
- Asymmetric syntheses with r-α -hydroxypropionaldehydeTetrahedron, 1977