Anabolic Steroid Effect on Hepatic Protein Synthesis in Patients with Liver Cirrhosis

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Abstract
The effect of short-term treatment of anabolic steroid on the patients with compensated liver cirrhosis was assessed by the study on the hepatic protein synthesis in vitro. The results indicated that the treatment decreased the specific activity of hepatic trichloroacetic acid soluble fraction and increased that of hepatic trichloroacetic acid ethanol soluble fraction. Clinical studies resulted in an improvement of serum protein pattern and BSP retention, but no effect on hepatic histology. The effect of anabolic steroid on chronic liver disease was analytically discussed.

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