Chromium-51 Ethylenediaminetetraacetate for Estimation of Glomerular Filtration Rate
- 20 May 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 152 (3725) , 1076-1077
- https://doi.org/10.1126/science.152.3725.1076
Abstract
Renal clearances of inulin and chromium-51 ethylenediaminetetraacetate were compared in sheep. In 41 clearance periods from five animals the mean clearance ratio of the chelate to inulin was 0.95 ± 0.03 (S.D.). Part of the difference between the two sets of results may have been due to binding of the metal chelate by plasma protein since 1.5 to 2 percent of chromium-51 ethylenediaminetetraacetate in plasma could not be removed by dialysis.Keywords
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