PENICILLIN IN THE PREVENTION AND TREATMENT OF CONGENITAL SYPHILIS

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Abstract
The treatment of the pregnant syphilitic woman and of the congenitally syphilitic infant with weekly injections of neoarsphenamine or mapharsen supplemented by a bismuth preparation, although eminently satisfactory from the standpoint of both preventive and curative medicine, still has several aspects in which improvement may be expected. These facts have led us to try penicillin in the treatment of these conditions with the hope that it might be possible to eliminate some of the deficiencies in present day therapy. Included among the factors in the prevention and treatment of congenital syphilis which we would like to see improved by the discovery and application of new drugs and new technics, the following may be mentioned: Arsenotherapy is relatively toxic. Although, generally speaking, arsenicals are well tolerated and safe to use in the average case,1 reactions do occur which interfere with treatment or at times preclude their use entirely, and

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