Hydrocephalus as a Sequel to Lymphocytic Choriomeningitis

Abstract
A case of lympho-cytic choriomeningitis in a 15-year-old white girl is described followed by the development of a non-communicating hydrocephalus. Diagnosis was established by immunologic study which showed a significant rise in the lymphocytic choriomeningitis complement-fixing antibody titer 3 weeks after the onset. The subsequent development of hydrocephalus was presumably due to a posterior fossa arachnoiditis secondary to the meningitis. Treatment of the hydrocephalus by ventriculo-mastoidostomy resulted in complete relief of symptoms. Neurologic sequelae following this type of meningitis are uncommon. A review of the literature reveals only 2 previously reported cases of arachnoiditis as a sequel of proven lymphocytic choriomeningitis.

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