Interaction of d, l-erythro- and d,l-threo-γ-fluoromethotrexate with human leukemia cell dihydrofolate reductase
- 1 December 1989
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 38 (23) , 4321-4325
- https://doi.org/10.1016/0006-2952(89)90532-7
Abstract
No abstract availableThis publication has 15 references indexed in Scilit:
- Metabolism of the diaminoantifolates: Biosynthesis and pharmacology of the 7-hydroxyl and polyglutamyl metabolites of methotrexate and related antifolatesPharmacology & Therapeutics, 1987
- Polyglutamation of methotrexate. Is methotrexate a prodrug?Journal of Clinical Investigation, 1985
- gamma-Fluoromethotrexate: synthesis and biological activity of a potent inhibitor of dihydrofolate reductase with greatly diminished ability to form poly-gamma-glutamates.Proceedings of the National Academy of Sciences, 1985
- OCCURRENCE AND SIGNIFICANCE OF D-METHOTREXATE AS A CONTAMINANT OF COMMERCIAL METHOTREXATE1984
- Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro.Journal of Biological Chemistry, 1982
- REVERSIBILITY OF HIGH-AFFINITY BINDING OF METHOTREXATE IN L1210 MURINE LEUKEMIA-CELLS1978
- Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemiaCancer, 1965