Anatomical pathways related to the clinical findings in aneurysms of the anterior communicating artery

Publisher Website
Google Scholar
Abstract
Extreme disturbances in function are produced by lesions due to aneurysms of the anterior communicating artery. In an attempt to find an explanation for these effects lesions were made in 7 Macaques in the parolfactory area and/or the anterior perforated area. Studies of Marchi degeneration demonstrated the known fact that this region is neuroanatomically connected to many other areas of the brain. The parolfactory area and anterior perforated substance have connections with the hippocampus via the fornix; with the hypothalamus via the medial forebrain bundle; and with the frontal, temporal, parietal, occipital and cingulate cortices via the cingulum. A lesion in this region will affect the normal neurological interconnections of these areas. The mental and behavioral aberrations seen clinically will reflect the degree of involvement and whether it is of a destructive or irritative nature.