CYTOLOGIC DETECTION OF MALIGNANT MESOTHELIOMA OF PERICARDIUM

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 22  (5) , 344-349
Abstract
A rare case of human malignant mesothelioma of the pericardium is reported, with the initial diagnosis made by cytology from the smears of the pericardial fluid. There were numerous large clusters in the smears, in which 2 types of cells were mixed: adenocarcinoma-like round cells and fibrosarcoma-like spindly cells. Some round cells resembled benign mesothelial cells. Central collagenous stalks and brush borders with long microvilli in the round cell aggregates were specific for carcinomatous mesothelioma and differentiated the round cells from adenocarcinoma cells. The spindly and pleomorphic tumor cells, present both singly and in clusters, implied malignancy. A preliminary cytologic diagnosis of probable mixed malignant mesothelioma was made. Histopathologic and EM examinations confirmed the cytologic description that this tumor was a malignant mesothelioma.

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