A comparative study of the protonation of myo-inositol hexakis(phosphate)
- 1 January 1986
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases
- Vol. 82 (6) , 1935-1943
- https://doi.org/10.1039/f19868201935
Abstract
Numerous studies of the protonation of myo-inositol hexakis(phosphate)(IP6) have lead to divergent results. Our values of the constants determined at 25 °C in 0.1 mol dm–3 Et4NClO4 or Bu4NBr media are sometimes several orders of magnitude higher than those previously published. The reason for the discrepancy between the results is found from an examination of the theoretical titration curves computed with the protonation constants measured in the presence of various support electrolytes at different ionic strengths. It is reasonable to suppose that complexation equilibria, involving alkali-metal cations, are superimposed on the protonation equilibria.This publication has 2 references indexed in Scilit:
- Preparation of low‐affinity red cells with dimethylsulfoxide‐mediated inositol hexaphosphate incorporation: Hemoglobin and ATP recovery using a continuous‐flow methodAmerican Journal of Hematology, 1984
- Conformational states of myo-inositol hexakis(phosphate) in aqueous solution. A carbon-13 NMR, phosphorus-31 NMR, and Raman spectroscopic investigationJournal of the American Chemical Society, 1980