Abstract
H. influenzae isolates from sputum of 111 patients with chronic bronchitis were tested for susceptibility to 8 antimicrobial drugs. A new .beta.-lactam, LY-127935, was the most active agent tested. Ampicillin, cefamandole, tetracycline and cefuroxime showed good activity against most isolates. Two strains, both nontypable, were resistant to ampicillin and produced .beta.-lactamase. Cefaclor was somewhat less effective, although most strains were susceptible. Erythromycin and cephalexin were of limited utility.

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