Preparation of Enantiomerically Enriched Compounds Using Enzymes; VII.1A Synthesis of Japanese Beetle Pheromone Utilizing Lipase-Catalyzed Enantioselective Lactonization
- 1 January 1990
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1990 (12) , 1112-1114
- https://doi.org/10.1055/s-1990-27105
Abstract
The Japanese beetle pheromone, (R,Z)-(-)-5-(1-decenyl)-2-oxo-tetrahydrofuran, was synthesized by means of the enzymatic enantioselective lactonization of the racemic key-intermediate methyl (RS)-4-hydroxy-5-tetradecynoate.Keywords
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