Prevention of Demasculinization and Feminization of the Brain in Prenatally Stressed Male Rats by Perinatal Androgen Treatment1)
- 1 January 1983
- journal article
- research article
- Published by Georg Thieme Verlag KG in Experimental and Clinical Endocrinology & Diabetes
- Vol. 81 (01) , 88-90
- https://doi.org/10.1055/s-0029-1210211
Abstract
Female rats were exposed to immobilization and illumination stress from day 15—22 of pregnancy. Their male offspring showed demasculinization, i.e. significantly decreased male sexual behaviour, and feminization, i.e. significantly increased female sexual behaviour, in adulthood. This permanent demasculinization and feminization of the brain, induced by prenatal stress, could be prevented by perinatal androgen treatment.Keywords
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