A novel synthesis of nucleoside 5′-triphosphates
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 18,p. 1276-1277
- https://doi.org/10.1039/c39910001276
Abstract
Facile syntheses of ribonucleoside 5′-triphosphates have been accomplished in good yield (>60%) in a one-pot reaction of unprotected nucleosides with phosphoryl chloride followed by treatment of the resulting phosphorodichloridate with tri-n-butylammonium phosphate in the presence of dimethylformamide.Keywords
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