Aging of the erythrocyte
- 31 July 1980
- journal article
- research article
- Published by Springer Nature in Annals of Hematology
- Vol. 41 (2) , 131-136
- https://doi.org/10.1007/bf01039656
Abstract
Mittels der Spinprobenmethode wurden die Veränderungen der Mikroviskosität von dichtgetrennten Rindererythrozyten untersucht. Die Verlängerung der Rotations-Korrelationszeit von Tempamine als einer Spinprobe belegt den Anstieg der Mikroviskosität im Erythrozyteninneren bei der in vivo-Alterung. Dieser Anstieg ist wahrscheinlich von Veränderungen des Elektrolytgehalts abhängig und kann den Verlauf von Diffusions-limitierten Reaktionen in der Zelle beeinflussen. By means of the spin labelling technique changes in the microviscosity of the cell interior of density-separated bovine red blood cells were estimated. An increase in the rotational correlation time of the Tempamine spin label indicated an increase in the microviscosity of the red blood cell interior during in vivo aging. This increase is apparently due to alterations in the electrolyte content and may influence the course of diffusion-limited reactions in the cell.This publication has 18 references indexed in Scilit:
- Superoxide dismutase activity decreases during erythrocyte agingCellular and Molecular Life Sciences, 1978
- Hydration and selfassociation of haemoglobin in solutionBiochemical and Biophysical Research Communications, 1978
- Use of the spin label tempamine for measuring the internal viscosity of red blood cellsBiochemical and Biophysical Research Communications, 1977
- Biochemical characterization of density-separated human erythrocytesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- AnnotationBritish Journal of Haematology, 1975
- The appearance of a protein in the human erythrocyte membrane during ageingFEBS Letters, 1974
- The effect of calcium on temperature-induced phase changes in liquid-crystalline cardiolipin structureBiochimica et Biophysica Acta (BBA) - Biomembranes, 1973
- Fluid Drop-Like Transition of Erythrocytes under ShearScience, 1969
- Metabolic dependence of red cell deformabilityJournal of Clinical Investigation, 1969
- Stratified Blood Sedimentation—Isolation of Immature Red CellsNature, 1938