Enforced adenoviral vector-mediated expression of HOXB4 in human umbilical cord blood cd34+ cells promotes myeloid differentiation but not proliferation
Open Access
- 1 October 2003
- journal article
- research article
- Published by Elsevier in Molecular Therapy
- Vol. 8 (4) , 618-628
- https://doi.org/10.1016/s1525-0016(03)00237-5
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Reduced Proliferative Capacity of Hematopoietic Stem Cells Deficient inHoxb3andHoxb4Molecular and Cellular Biology, 2003
- The Competitive Nature of HOXB4-Transduced HSC Is Limited by PBX1: The Generation of Ultra-Competitive Stem Cells Retaining Full Differentiation PotentialImmunity, 2003
- High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiationBlood, 2003
- Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cellsBlood, 2002
- Adenoviral vector design for high-level transgene expression in primitive human hematopoietic progenitorsGene Therapy, 2000
- Diversification of haematopoietic stem cells to specific lineagesNature Reviews Genetics, 2000
- Efficient Adenoviral Vector Transduction of Human Hematopoietic SCID-Repopulating and Long-Term Culture-Initiating CellsHuman Gene Therapy, 2000
- The Role of HOX Homeobox Genes in Normal and Leukemic HematopoiesisThe International Journal of Cell Cloning, 1996
- Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo.Genes & Development, 1995
- GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts.Genes & Development, 1995