RULE OF ANTIBODY STRUCTURE - PRIMARY STRUCTURE OF A HUMAN MONOCLONAL IGAL-IMMUNOGLOBULIN (MYELOMA PROTEIN TRO) .2. CLEAVAGE OF MONOMER IGA-MOLECULE AND REDUCED AND ALKYLATED H-CHAIN AND L-CHAIN BY CYANOGEN-BROMIDE

1 January 1978

journal article
research article

Vol. 359 (12) , 1689-1695

Abstract

The monomer of myeloma protein Tro and the reduced and alkylated H and L chains were cleaved by cyanogen bromide [CNBr]. All CNBr fragments were isolated and characterized by amino acid analyses, end-group and MW determinations. The smaller fragments of the 5 H chain fragments were split with trypsin. The peptides were isolated and their primary structure was determined.

This publication has 2 references indexed in Scilit:

RULE OF ANTIBODY STRUCTURE - PRIMARY STRUCTURE OF A HUMAN MONOCLONAL IGAL-IMMUNOGLOBULIN (MYELOMA PROTEIN TRO) .5. ARRANGEMENT OF TRYPTIC PEPTIDES AND A DISCUSSION OF COMPLETE PRIMARY STRUCTURE OF H-CHAIN
1978
[8] End-group analysis using dansyl chloride
Published by Elsevier ,1972