Definition of the HL A‐Aw43 antigen
- 1 January 1989
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 33 (1) , 41-44
- https://doi.org/10.1111/j.1399-0039.1989.tb01676.x
Abstract
The HLA antigen Aw43 has been observed only in Southern African populations. In order to confirm its identity and clarify its definition, ten cells with this specificity were shipped to laboratories in England, the United States of America and Australia to be tested with the sera from the 10th International Histocompatibility Workshop. The results of tests on nine of these cells which were sufficiently viable indicated that HLA-Aw43 is a distinct serological specificity which could be distinguished from both the A10 cross-reacting group (A25, A26 and Aw34) and A29. The Aw43 specificity segregated in two South African Negro families, and occurred commonly in association with Bw70. The occurrence of HLA-Aw43 in South African Caucasoids, in contrast to its absence in other Caucasoid groups, is probably due to genetic admixture with indigenous South African population.This publication has 3 references indexed in Scilit:
- HLA-A, B, C, DR and DQ polymorphisms in three South African population groups: South African Negroes, Cape Coloureds and South African CaucasoidsTissue Antigens, 1988
- Antigen Report: HLA-Aw43Published by Springer Nature ,1984
- A Reassessment of the HL-A System in Khoisan Populations of South West AfricaTissue Antigens, 1975