The Phosphatidylinositol 3-Kinase/Akt Pathway Enhances Smad3-stimulated Mesangial Cell Collagen I Expression in Response to Transforming Growth Factor-β1
Open Access
- 1 January 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (4) , 2632-2639
- https://doi.org/10.1074/jbc.m310412200
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Cross‐talk between ERK MAP kinase and Smad‐signaling pathways enhances TGF‐β dependent responses in human mesangial cellsThe FASEB Journal, 2003
- Activin/TGF-β induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIPNature Cell Biology, 2002
- Requirement of BMP-2-induced Phosphatidylinositol 3-Kinase and Akt Serine/Threonine Kinase in Osteoblast Differentiation and Smad-dependent BMP-2 Gene TranscriptionJournal of Biological Chemistry, 2002
- The Phosphoinositide 3-Kinase PathwayScience, 2002
- Sp1 and Smad Proteins Cooperate to Mediate Transforming Growth Factor-β1-induced α2(I) Collagen Expression in Human Glomerular Mesangial CellsPublished by Elsevier ,2001
- A mechanism of repression of TGFbeta / Smad signaling by oncogenic RasGenes & Development, 1999
- Human Smad3 and Smad4 Are Sequence-Specific Transcription ActivatorsPublished by Elsevier ,1998
- Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cellsProceedings of the National Academy of Sciences, 1997
- TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4The EMBO Journal, 1997
- Partnership between DPC4 and SMAD proteins in TGF-β signalling pathwaysNature, 1996