Acceleration of Tibia and Distal Radius Fracture Healing in Patients Who Smoke
- 1 April 1997
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Clinical Orthopaedics and Related Research
- Vol. 337 (337) , 198-207
- https://doi.org/10.1097/00003086-199704000-00022
Abstract
A low intensity ultrasound device was investigated as an accelerator of cortical and cancellous bone fracture healing in smokers and non-smokers. Statistically significant reductions in healing time for smokers and nonsmokers were observed for tibial and distal radius fractures treated with an active ultrasound device compared with a placebo control device. The healing time for a tibial fracture was reduced 41% in smokers and 26% in nonsmokers with the active ultrasound device. Similarly, distal radius fracture healing time was reduced by 51% in smokers and 34% in nonsmokers with the active device. Treatment with the active ultrasound device also substantially reduced the incidence of tibial delayed unions in smokers and nonsmokers. The use of the active ultrasound device accelerates cortical and cancellous bone fracture healing, substantially mitigates the delayed healing effects of smoking, speeds the return to normal activity, and reduces the long-term complication of delayed union.This publication has 27 references indexed in Scilit:
- Fibrous union of the mandible: A review of 27 patientsJournal of Oral and Maxillofacial Surgery, 1994
- Nicotine on the Revascularization of Bone GraftSpine, 1994
- Cigarette Smoking and Nonunion after Ankle ArthrodesisFoot & Ankle International, 1994
- Acceleration of tibial fracture-healing by non-invasive, low-intensity pulsed ultrasound.Journal of Bone and Joint Surgery, 1994
- Surgical Treatment of Isthmic Lumbosacral SpondylolisthesisSpine, 1989
- The Role of Anterior Lumbar Fusion for Internal Disc DisruptionSpine, 1988
- Prostacyclin production by the heart: Effect of nicotine and carbon monoxideJournal of Vascular Surgery, 1987
- The Rate of Pseudarthrosis (Surgical Nonunion) in Patients Who Are Smokers and Patients Who Are Nonsmokers: A Comparison StudySpine, 1986
- Clinical Pharmacology of NicotineAnnual Review of Medicine, 1986
- Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bonesJournal of Bone and Joint Surgery, 1976