Familial balanced (7;11;21)translocation and Down's syndrome in two siblings
- 23 April 1975
- journal article
- Published by Wiley in Clinical Genetics
- Vol. 7 (4) , 304-307
- https://doi.org/10.1111/j.1399-0004.1975.tb00333.x
Abstract
Cytogenetic studies of a family with two children with Down's syndrome have revealed a balanced reciprocal translocation between chromosomes No. 7, 11 and 21 in the mother. One of three daughters has inherited this translocation; two mongoloid daughters have a supernumerary chromosome No. 21 in addition to the translocation.Keywords
This publication has 7 references indexed in Scilit:
- An Analysis of the Break Points of Structural Rearrangements in ManJournal of Medical Genetics, 1974
- Rare Translocation 47, XY, t(12;21) in Down’s SyndromeHuman Heredity, 1974
- Localization of heterochromatin in human chromosomesCytogenetic and Genome Research, 1971
- Identification of human chromosomes by DNA-binding fluorescent agentsChromosoma, 1970
- RECIPROCAL TRANSLOCATIONSBritish Medical Bulletin, 1969
- Chromosome preparations of leukocytes cultured from human peripheral bloodExperimental Cell Research, 1960