Atrazine in Plasma and Tissue Following Atrazine-Aminotriazole-Ethylene Glycol-Formaldehyde Poisoning
- 1 January 1993
- journal article
- case report
- Published by Taylor & Francis in Journal of Toxicology: Clinical Toxicology
- Vol. 31 (2) , 323-331
- https://doi.org/10.3109/15563659309000399
Abstract
A high performance liquid chromatography method has been used to study the plasma kinetics of atrazine in a human fatality after ingestion of a herbicide mix containing atrazine, aminotriazole, ethylene glycol and formaldehyde. A hemodialysis was performed in an effort to eliminate these toxic substances. The mean atrazine clearance over 4 h was 250 mL/min and the dialysance of atrazine was calculated as 76%. On autopsy, the kidney showed the highest concentration of atrazine (97.62 micrograms/g-1 wet tissue) with lesser concentrations in the lung, small intestine and liver, and the lowest concentration in the heart.Keywords
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