Chiral Phosphoromorpholidate Derivatives of Oligothymidylate and Their Hybridization Abilities
- 1 February 1992
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 11 (2-4) , 473-482
- https://doi.org/10.1080/07328319208021719
Abstract
Interactions of diastereomerically pure phosphoromorpholidate analogs of oligothymidylate with poly(dA) were examined. Obvious differences between diastereomers appeared in duplex formation and tentative stereochemical characterizations of them were done.Keywords
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