Prevalence of multiple antibiotic resistance in Neisseria gonorrhoeae.
Open Access
- 1 December 1976
- journal article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 52 (6) , 384-386
- https://doi.org/10.1136/sti.52.6.384
Abstract
The susceptibility of 100 strains of Neisseria gonorrhoeae to five antimicrobial agents (penicillin, streptomycin, oxytetracycline, sulphamethoxazole, and gentamicin) was examined. Three strains were resistant to each antimicrobial, fourteen exhibited resistance to three or four of the five compounds tested, and 49 were resistant to a single agent, or to pairs of the selected agents. 34 strains were found to be fully sensitive to all of the compounds tested. It is suggested that resistance to gentamicin and sulphamethoxazole may be determined by a multiple resistance gene. The overall frequency of penicillin resistance was found to be 26-5 per cent (MIC greater than 0-06 mug/ml.), suggesting a significant decrease in resistance since 1968.Keywords
This publication has 17 references indexed in Scilit:
- Activity of eight antimicrobial agents in vitro against N. Gonorrhoeae.Sexually Transmitted Infections, 1975
- Antibiotic susceptibility of Neisseria gonorrhoeae isolated in the Western Pacific in 1971.Sexually Transmitted Infections, 1975
- Neisseria meningitidis in urogenital infection.Sexually Transmitted Infections, 1974
- Vancomycin-sensitive strains of Neisseria gonorrhoeae. A problem for the diagnostic laboratory.Sexually Transmitted Infections, 1973
- Multiple Antibiotic Resistance due to a Single Mutation in Neisseria gonorrhoeaeThe Journal of Infectious Diseases, 1973
- Single-session treatment of uncomplicated gonorrhoea in men, using penicillin combined with cotrimoxazole. Controlled trial comparing four different treatment schedules with observations on antibiotic sensitivities of gonococci and a review of the literature.Sexually Transmitted Infections, 1973
- Trimethoprim as an additional selective agent in media for the isolation ofN. gonorrhoeaeJournal of Clinical Pathology, 1970
- IN-VITRO ACTIVITY OF TWELVE ANTIBACTERIAL AGENTS AGAINST NEISSERIA GONORRHήThe Lancet, 1970
- The problem of penicillin resistant gonococci.Sexually Transmitted Infections, 1968
- A Comparison of the in vitro Sensitivity of Gonococci to Penicillin with the Results of TreatmentSexually Transmitted Infections, 1958