ANKYLOSING-SPONDYLITIS WITH SELECTIVE IGA DEFICIENCY AND A CIRCULATING ANTICOAGULANT

  • 1 January 1977
    • journal article
    • research article
    • Vol. 4  (3) , 297-302
Abstract
A patient with ankylosing spondylitis had selective Ig[immunoglobulin]A deficiency and a non-heparin, immediate-acting antithrombin (antithrombin V). T [thymus derived] cells were decreased, and serum IgG was increased. In vitro synthesis of IgG by peripheral blood lymphocytes was very high. This association of ankylosing spondylitis with the T cell and protein abnormalities is probably fortuitous but does demonstrate that severe spondylitis may evolve in the absence of IgA.

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