Work in progress: serial evaluation of tumor volume using computed tomography and contrast kinetics.

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Abstract
Computed tomography can be used to evaluate tumor volume changes after therapy. Pre- and posttreatment results are presented for 9 human neoplasms. Volume changes are correlated with the behavior of i.v. diatrizoate contrast material. The 5-minute diatrizoate distribution volume appears to be a potential contrast material marker for therapeutically induced tumor volume changes. Neoplasms decreasing in volume demonstrate a decrease in the diatrizoate distribution volume; those increasing in volume demonstrate an increase.

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