Active synthesis of collagen by albumin-producing liver parenhymal cell clones in culture.
- 1 January 1978
- journal article
- Published by Japan Academy in Proceedings of the Japan Academy, Series B
- Vol. 54 (7) , 391-396
- https://doi.org/10.2183/pjab.54.391
Abstract
Two lines of albumin-producing rat liver parenchymal cell clones (BB and BC) have been shown to synthesize collagen at a level of 1-2% of total proteins produced which was two to nine times higher than those by the fibroblastic cells (L-929 and RLG-1). Type analysis of the collagen by carboxymethylcellulose chromatography has shown that the former two cell lines synthesized type I collagen, [α1(I)]2α2, type X, composed of α1 chains and type Y similar to type III collagen, while a transformed liver cell line (M) did the former two collagen types.Keywords
This publication has 0 references indexed in Scilit: