Alcohol‐induced switching over of metabolic flux in Streptomyces noursei JA0 3890b
- 1 January 1979
- journal article
- research article
- Published by Wiley in Journal of Basic Microbiology
- Vol. 19 (10) , 721-726
- https://doi.org/10.1002/jobm.19790191006
Abstract
Short‐chain alcohols, benzyl alcohol and Tween 20 were found capable of switching over the metabolic flux in Streptomyces noursei JA 3890b from the preference of oxidative deamination of alanine towards the reinforced acquisition of NH. These changes were correlated to the decrease of the ratio of saturated to olefinic fatty acids in the mycelium, suggesting that alcohols and other polar lipophilic compounds can interfere with the biosynthesis and the function of the cytoplasmic membrane in Streptomyces.Keywords
This publication has 12 references indexed in Scilit:
- Regulative influence of o‐aminobenzoic acid on the biosynthesis of nourseothricin in cultures of Streptomyces noursei JA 3890b IV. Bistability of metabolism and the mechanism of action of aminobenzoic acidsJournal of Basic Microbiology, 1979
- Regulative influence ofo-aminobenzoic acid on the biosynthesis of nourseothricin in cultures ofStreptomyces noursei JA 3890b IV. Bistability of metabolism and the mechanism of action of aminobenzoic acidsJournal of Basic Microbiology, 1979
- Lipids of the streptomycetes structural investigation and biological interrelationChemistry and Physics of Lipids, 1978
- Mechanism of ethanol-induced changes in lipid composition of Escherichia coli: inhibition of saturated fatty acid synthesis in vivoBiochemistry, 1978
- Regulative influence of o‐aminobenzoic acid on the biosynthesis of nourseothricin in cultures of Streptomyces noursei JA 3890b III. Change of redox state of nicotinamide‐adenine‐dinucleotides in the presence of aminobenzoic acidsJournal of Basic Microbiology, 1978
- Regulative influence ofo-aminobenzoic acid on the biosynthesis of nourseothricin in cultures ofStreptomyces noursei JA 3890b III. Change of redox state of nicotinamide-adenine-dinucleotides in the presence of aminobenzoic acidsJournal of Basic Microbiology, 1978
- Biosynthesis of candicidin by phosphate-limited resting cells ofStreptomyces griseusApplied Microbiology and Biotechnology, 1976
- Microbial production of amphotericin B-3H and the synthesis of its sodium desoxycholate (carboxyl-14C) complex and methyl-14C-ester.The Journal of Antibiotics, 1976
- Alteration of the unsaturated to saturated ratio of fatty acids in bacterial lipids by alcohols.Agricultural and Biological Chemistry, 1975
- Alteration of Permeability for the Release of Metabolites from the Microbial CellPublished by Springer Nature ,1968