Further evaluation of the biphasic kinetics of iron removal from transferrin by 3,4-LICAMS

Abstract
Further evaluation of the kinetic data for Fe3+ removal from isolated differic and monoferric transferrins by the tricatechol ligand 3,4-LICAMS has allowed full characterization of the four microscopic rate constants. A very small cooperativity exists between the two iron-binding sites with respect to their rates of iron release. The activation free energy profile for the system is presented.